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Mega GLA with Sesame Lignans
#2-00756

Mega GLA with Sesame Lignans

Life Extension
Retail Price: $19.50
Our Price: $14.63    25% Off
Quantity: 
Package: 60 softgels
Availability: Item generally ships in 24-48 hours.
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OVERVIEW SUPPLEMENT FACTS REVIEWS (0)
As people age, chronic systemic inflammation can inflict degenerative effects throughout the body. A primary cause of this destructive cascade is the production of cell-signaling chemicals known as inflammatory cytokines. Along with these dangerous cytokines, imbalances of hormone-like messengers called prostaglandins also contribute to chronic inflammatory processes.
The body needs fatty acids to survive and is able to make all but two of them: linoleic acid, in the omega-6 family and linolenic acid, in the omega-3 family. These two fatty acids must be supplied by the diet and are therefore considered essential fatty acids (EFAs).
Omega-3 fatty acids, found in cold-water fish (and fish oil), and perilla and flaxseed oils, can be part of a healthy diet. Omega-3 oils contain the essential fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are usually lacking in the typical Western diet that includes high amounts of omega-6 fats.
Omega-6 fatty acids are well supplied in the diet by meat and vegetable oils. However, not all omega-6 fatty acids are of equal value. Gamma linolenic acid (GLA), found in evening primrose oil, borage oil, and black currant oil is an important fatty acid that plays a beneficial role in healthy prostaglandin formation. What you eat also contributes to the production of inflammatory cytokines. Eating foods cooked at high temperature can cause the formation of advanced glycation end (AGE) products. Glycation is the binding of a protein molecule to a glucose molecule that results in the formation of damaged protein structures. As the damaged proteins accumulate, they activate the production of inflammatory cytokines. Presently there is no way to reverse the effects of glycation.
Health conscious people have been consuming a lot of borage oil to obtain GLA (gamma-linolenic acid), the parent of the biologically active DGLA (di-homo-gamma-linolenic acid). Life Extension has added 10 milligrams of sesame lignans to each capsule of Mega GLA borage oil. Sesame lignans not only increase beneficial DGLA, but they also help reduce production of pro-inflammatory arachidonic acid, which decreases the formation of destructive prostaglandin E2 and leukotriene B4.
Numerous studies document GLA’s multiple health effects, but new information about the ability of sesame to prevent the conversion of GLA into arachidonic acid indicates that many more people may now be able to benefit from supplemental GLA.
Supplement Facts
Serving Size 1 softgel
Servings Per Container 60
Amount Per Serving
Calories
12
Calories from fat
12
Total Fat
1.3 g
Saturated fat
0.25 g
Monounsaturated fat
0.25 g
Polyunsaturated fat
0.8 g
Borage seed oil (Borago officinalis)
1300 mg
Gamma-linolenic acid (GLA)
285 mg
Sesame seed (Sesamum indicum) lignan extract [standardized to 60% sesamin (6 mg)]
10 mg
Other ingredients: magnesium stearate, gelatin and water.
This product contains NO sugar, yeast, wheat, gluten, corn, soy or dairy. Contains NO artificial color, sweeteners, flavors or preservatives.
Dosage and Use
- Take one softgel one to two times daily or as recommended by a healthcare practitioner.
- Up to five softgels can be taken daily.
- This product is best utilized when taken with food.
Caution
Those taking anticoagulant drugs like Coumadin® (warfarin) should inform their doctor that they are taking GLA, EPA, or DHA supplements, as the physician may want to adjust the dose of anticoagulant medication based on tests that measure coagulation factors such as template bleeding time.
Since GLA, EPA, and DHA interfere with blood clotting, those who suffer from any type of hemorrhagic disease related to excessive bleeding or blood vessel leakage should consult their physician before supplementing these fatty acids.
This product should not be used by individuals who have an allergy to sesame.
Warnings
- Keep out of reach of children.
- Do not exceed recommended dose.
- Do not purchase if outer seal is broken or damaged.
- If you have a bad reaction to product discontinue use immediately.
- When using nutritional supplements, please inform your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

 
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The Doctor's Corner
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After practicing Integrative Medicine for over 20 years, it naturally appears to me that rationally combining a healthy lifestyle, nutrition, vitamins, supplements and pharmaceuticals helps achieve the best results for a healthy well-being...
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